Metabolism, modelled and engineered.

The Computational Metabolic Engineering research group uses model-driven analysis of experimental data to understand, predict and engineer metabolism, for planetary health through sustainable microbial cell factories and for human health through precision medicine.

What we work on

Modelling

Modelling tools

Software for genome-scale and resource allocation models, so predicted fluxes respect what the cell can afford to make.

Data

Omics meets models

Transcriptomics and proteomics interpreted through enzyme-constrained models to explain a phenotype.

Planetary health

Cell factories

Model-guided engineering of microbes, mainly Yarrowia lipolytica, for sustainable chemicals.

Human health

Human metabolism

Human genome-scale models combined with patient and single-cell data for precision medicine.

GECKO

Turns a genome-scale model into an enzyme-constrained model, using kinetic and proteomics data.

RAVEN

Reconstruct, curate and simulate genome-scale metabolic models.

Metabolic Atlas

Web portal to browse, search and visualise genome-scale models.

Models

A selection of models (co-)developed by us

Recent papers and preprints

Google Scholar →

Ten most recent, from Europe PMC, Crossref and bioRxiv, 29 October 2026. Preprints are only listed until they appear in a journal.

Teaching

Join us or collaborate

We're always happy to hear from people who share our interest in metabolism, modelling and engineering. A few things are useful to know before you get in touch.

Student projects

Please note that we don't take on Master's thesis projects shorter than one semester (5 to 6 months).

PhD and postdoc positions

All open positions are advertised on the Chalmers vacancies page. Apply there; no listing means no open position.

Research visits and collaborations

These restrictions don't apply to short visits by PhD students and postdocs, or to collaborations. Get in touch.

Collaborative projects

A selection of the collaborative projects we take part in